The short answer

Botox usually lasts 3 to 4 months for frown lines, forehead lines and crow's feet. That matches the FDA label for Botox Cosmetic, which lists about 3 to 4 months for frown lines. Small doses wear off sooner: a lip flip lasts about 2 to 3 months. Underarm Botox for sweating lasts longest, about 6 months.

Botox takes about 1 to 2 weeks to fully kick in. Lines start to soften in 3 to 7 days, with full results at 10 to 14 days. When it wears off, movement returns gradually over weeks, not overnight.

How long Botox lasts in each area

Most face areas last about 3 to 4 months, the lips last about 2 to 3 months and the underarms about 6 months. The difference comes down to the size of the muscle, how much it moves and the dose.

Area	Typical dose at Cosmetica	How long it lasts	Where the number comes from
Frown lines (the 11s)	20 units	About 3 to 4 months	Botox Cosmetic FDA label
Forehead lines	20 units, treated with frown lines	About 3 to 4 months	Our Botox treatment page
Crow's feet	24 units (12 per side)	About 3 to 4 months	Our Botox treatment page
Lip flip	4 to 6 units	About 2 to 3 months	Our lip flip treatment page
Baby Botox (lighter dose)	About 5 to 10 units per area	Usually shorter than a full dose	Carruthers dose-ranging trial, 2005
Masseter (jaw slimming)	At least 25 units per side, 50 minimum	About 3 to 4 months	Our masseter Botox page
Underarm sweating	100 units (50 per side)	About 6 months (median 201 days in the FDA studies)	Botox FDA label

The lip flip fades fastest because the muscle around the mouth moves constantly and only a few units are used. Underarm Botox works on sweat glands rather than a facial muscle, and it lasts the longest. See masseter Botox for jaw slimming and clenching.

How long each neurotoxin lasts, by FDA label and trial

Botox, Dysport, Xeomin and Jeuveau all last roughly 3 to 4 months, and Daxxify lasted a median of about 6 months in its trials. Here's what each FDA label or pivotal trial reports for frown lines.

Neurotoxin	Label dose for frown lines	What the label or trial reports	Source	Price at Cosmetica
Botox	20 units	Effect lasts about 3 to 4 months. At day 120, 25% of treated people were still rated as responders by investigators	Botox Cosmetic FDA label	$9.99 per unit
Dysport	50 Dysport units	Effect may last up to 4 months. At day 120, 23% to 29% still had none or mild frown lines	Dysport FDA label (studies GL-1 and GL-3)	$199 per area
Xeomin	20 units	Typical effect lasts up to 12 to 16 weeks	Xeomin FDA label	$9.99 per unit
Jeuveau	20 units	67% to 71% responded at day 30, and the benefit over placebo was still measurable at day 150	Jeuveau FDA label; EV-001 and EV-002 trials (Beer et al., 2019)	$9.99 per unit
Daxxify	40 units	Median of 24.0 and 23.9 weeks with none or mild frown lines; 27.7 and 26.0 weeks to return to baseline	SAKURA 1 and SAKURA 2 trials (Carruthers et al., 2020)	$9.99 per unit

Each trial measured results a little differently, so compare the ranges rather than the decimals. Units also aren't interchangeable between brands. Dysport uses more units for the same area, which is why we price it by the area. For how the products feel and spread, see Botox vs. Dysport vs. Xeomin.

First-timers vs. regulars

Your first treatment may wear off a little sooner than later ones. The American Society of Plastic Surgeons notes that first-time results can be shorter and often improve after a second treatment.

There's a practical reason too. At your first visit, your injector recommends a dose after watching how your face moves, and any touch-up is handled case by case. Regulars are dosed based on what their muscles needed before. Some people who treat the same areas on schedule find their results last a little longer. Read your first Botox appointment for what to expect on day one.

What makes Botox wear off sooner or last longer

Dose, muscle strength and product choice matter most. These are the factors with real evidence behind them:

Dose. Carruthers and colleagues compared doses for frown lines in a 2005 trial of 80 women. At 4 months, lines had returned in 83% of people given 10 units, compared with 33% given 20 units.
Muscle strength. Stronger muscles need more units for the same result. Men usually need about 5 to 10 more units per area.
The area. Small muscles that move all day, like the lips, wear off sooner than the frown lines or forehead.
The product. Daxxify lasted a median of about 6 months for frown lines in the SAKURA trials, longer than the other labels report.
Timing between treatments. The Botox label says the chance of forming antibodies may be minimized by using the lowest effective dose at the longest feasible intervals. In its crow's feet trials, none of 916 people developed neutralizing antibodies.

You'll also read online that exercise, a fast metabolism or zinc supplements change how long Botox lasts. Those claims don't come from the FDA labels or the large trials above, so we plan around dose, product and timing instead. Following your aftercare helps the Botox settle where it was placed.

When to rebook

Most people rebook every 3 to 4 months, when they notice movement starting to return. Here's a typical timeline after a treatment:

Days 3 to 7: lines start to soften.
Days 10 to 14: full results. This is the time for a check-in if you'd like a small adjustment. Touch-up units are $9.99 each and handled case by case.
Months 2 to 3: a lip flip starts to fade.
Months 3 to 4: movement gradually returns in the forehead, frown lines and crow's feet. Book your next visit to keep results consistent.
About month 6: underarm results usually fade.

Don't book sooner than 3 months for a full re-treatment. The Botox Cosmetic label says dosing more often than every 3 months hasn't been clinically evaluated. The Dysport, Xeomin, Jeuveau and Daxxify labels say not to re-treat more often than every 3 months.

What Botox costs per year at $9.99 per unit

One area of Botox costs about $600 to $800 a year at Cosmetica, based on 20 units at $9.99 per unit and 3 to 4 visits. Here's how common plans add up:

Plan	Cost per visit	Visits per year	Cost per year
One area, 20 units of Botox	$199.80	3 to 4	About $600 to $800
Average visit, 40 to 50 units	About $400 to $500	3 to 4	About $1,200 to $2,000
Dysport, one area	$199	3 to 4	About $600 to $800
Daxxify, frown lines at the 40-unit label dose	About $400	About 2	About $800
Lip flip, 4 to 6 units	$199	4 to 6	About $800 to $1,200
Masseter, 50 units	About $500	3 to 4	About $1,500 to $2,000
Underarm sweating, 100 units	About $999	About 2	About $2,000

Your injector confirms your exact dose and price before anything is done. A $100 deposit is collected when you book and credited to your treatment. For prices by area, see our Botox cost guide. Payment plans are available through Cherry and CareCredit; see financing.

What happens when Botox wears off

Nothing dramatic. Over 3 to 4 months, your muscles gradually move the way they did before, and lines return to how they'd have looked without treatment. You won't look older than you would have, and you can restart any time.

Questions we hear

Does Botox last longer the more you get it?

It can. The American Society of Plastic Surgeons notes results often improve after the first treatment, and some regulars find their results last a little longer. Your dose and how strong your muscles are still matter most.

How long does Botox last in the forehead?

About 3 to 4 months. The forehead is usually treated together with the frown lines, which the FDA label doses at 40 units in total.

How long does Dysport last compared with Botox?

About the same. The Dysport label says its effect may last up to 4 months, and the Botox Cosmetic label says about 3 to 4 months.

Does Daxxify really last 6 months?

In the SAKURA 1 and 2 trials, half of people still had none or mild frown lines at about 24 weeks, roughly 6 months. Individual results vary, and Daxxify is $9.99 per unit at Cosmetica.

Can I get Botox again before 3 months?

A small adjustment at your 2-week check-in is common. A full re-treatment should wait at least 3 months, per the FDA labels.

Why did my Botox seem to wear off early?

The usual reasons are a light dose, strong muscles or a first treatment. Book a check-in and your injector can adjust your dose or suggest a different product.

How long does baby Botox last?

Usually a little less than a full dose, because fewer units are used. See what baby Botox is for units, cost and timing.

Ready to plan your next visit? Book a Botox appointment or call us at (561) 621-1578. Every treatment is overseen by our medical director, Dr. Andrei Gherghina, a board-certified dermatologist.

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