NAD+ IV therapy delivers NAD+, a coenzyme your cells use to make energy, directly into your bloodstream. At Cosmetica Med Spa in Boca Raton, NAD+ is The Highland on our IV drip menu: $399 for 250 mg or $599 for 500 mg, infused slowly over 2 hours or more by licensed medical professionals after a health screening. Research on NAD+ IV therapy is still early, and your provider will tell you honestly whether it fits your goals. Nothing is pushed. We're open 7 days a week, 8am to 8pm.
NAD+ at Cosmetica: The Highland
On our IV drip menu, NAD+ is The Highland, named for Highland Beach. Choose 250 mg or 500 mg, or get NAD+ 250 mg inside The Royal Palm Reserve along with fluids and vitamins.
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell. Your cells use it to turn food into energy and to help repair DNA. Your body makes it from vitamin B3 (niacin) and related nutrients, which is why it's sometimes linked to the B vitamins (see the National Institutes of Health fact sheet on niacin). Research shows NAD+ levels in many tissues fall as we get older, which is why it gets so much attention in healthy aging research (see this review published through the National Library of Medicine).
Why people book NAD+ IV therapy
Clients in Boca Raton usually ask about NAD+ for:
- Energy during a demanding stretch at work or home
- Mental focus and clarity
- Recovery after training, travel or a long week
- Healthy aging and overall wellness goals
These are the goals people come in with, not proven results. NAD+ isn't a treatment for any disease, and it doesn't replace care from your own doctor.
What the research says so far
We'd rather tell you what's known than oversell it. NAD+ itself is well studied in the lab. NAD+ given by IV has only been studied in small, early trials:
- A 2019 pilot study infused NAD+ slowly over 6 hours in healthy adults. Blood NAD+ levels didn't change until after the first 2 hours, one reason infusions are given slowly (Frontiers in Aging Neuroscience, 2019).
- A small 2024 pilot trial of 500 mg NAD+ IV found the infusion averaged about 3 hours, and most people felt temporary effects such as nausea, chest tightness or cramping. It hasn't yet been peer reviewed (medRxiv preprint, 2024).
- No large trials have shown that NAD+ IV therapy improves energy, focus or aging, and NAD+ infusions aren't FDA approved to treat any condition.
If you're curious and healthy, NAD+ can be a reasonable thing to try with a medical team. If you want a drip with clearer benefits for hydration, our IV therapy menu or a vitamin shot may fit better, and your provider will tell you honestly.

250 mg, 500 mg or The Royal Palm Reserve?
| The Highland 250 mg | The Highland 500 mg | The Royal Palm Reserve | |
|---|---|---|---|
| NAD+ | 250 mg | 500 mg | 250 mg |
| Also includes | NAD+ in IV fluids | NAD+ in IV fluids | The Royal Palm drip, anti-heartburn medication and an extra liter of fluids |
| Typical time | About 2 hours | 2 hours or more | 2 hours or more |
| Good for | A first NAD+ visit | People who've done NAD+ before | NAD+ plus hydration and vitamins in one visit |
| Price | $399 | $599 | $649 |
Your NAD+ visit, step by step
- Book online or call. A $100 deposit holds your time and is credited to your visit. Plan for 2 to 3 hours, or longer at 500 mg.
- Get ready. Eat a light meal, drink water and bring a list of your medications and supplements. Bring something to read or work on.
- Health screening. Your provider reviews your health history, medications and goals, and confirms your dose.
- IV placement. A small, flexible catheter is placed in your arm. Most people feel a quick pinch.
- A slow infusion. NAD+ is started slowly and adjusted to how you feel. Tell your provider if you feel flushing, chest tightness, nausea or cramping. Slowing the drip usually eases it within minutes.
- Back to your day. You can usually drive yourself home and go back to normal activities. See the full IV therapy aftercare.
Side effects and safety
Common, temporary effects during the infusion include flushing or warmth, chest or stomach tightness, nausea, cramping, headache and the urge to use the bathroom. They're usually tied to the drip rate and settle when it's slowed. Mild bruising at the IV site can happen and fades in a few days.
NAD+ isn't right for everyone. Let us know if you're pregnant or breastfeeding, are being treated for cancer, have heart, kidney or liver disease, or take medications that affect blood pressure. Your screening is there to keep you safe, and your provider may recommend something else.
NAD+ IV vs. NAD+ supplements vs. an IV drip
| NAD+ IV (The Highland) | Oral supplements (NR, NMN) | IV drip (The Boca and others) | |
|---|---|---|---|
| What it is | NAD+ itself, infused into a vein | Building blocks your body turns into NAD+ | Fluids plus vitamins and minerals |
| Time | 2 hours or more | A daily capsule | 30 to 60 minutes |
| Medical supervision | Yes | No | Yes |
| Hydration | Some | No | Yes |
| At Cosmetica | $399 or $599 | Not sold here | From $199 (see the drip menu) |
NAD+ IV therapy cost in Boca Raton
| Treatment | Price |
|---|---|
| The Highland, NAD+ 250 mg | $399 |
| The Highland, NAD+ 500 mg | $599 |
| The Royal Palm Reserve (includes NAD+ 250 mg) | $649 |
Your provider confirms your price before your infusion starts. NAD+ IV therapy is a cash-pay wellness service, and we don't bill insurance. Payment plans are available through Cherry and CareCredit. See starting prices for every treatment on our pricing page.
NAD+ IV therapy near Delray Beach, Boynton Beach and Deerfield Beach
Our Boca Raton location at 4400 N Federal Hwy, Suite 150, in the Sanctuary Shoppes with free parking, is a short drive from Highland Beach, Delray Beach, Boynton Beach and Deerfield Beach. See IV therapy near Delray Beach, IV therapy near Boynton Beach and IV therapy near Deerfield Beach.
When can you work out, drink alcohol or wear makeup? Our aftercare guide covers exactly what to do and avoid.
See the aftercare guide →Frequently asked questions
What is NAD+ IV therapy?
It's an infusion of NAD+, a coenzyme your cells use to make energy, given slowly through an IV. At Cosmetica it's The Highland on our drip menu, and it's given by licensed medical professionals after a health screening.
How much is NAD+ IV therapy in Boca Raton?
At Cosmetica Med Spa, NAD+ is $399 for 250 mg or $599 for 500 mg. The Royal Palm Reserve, which includes NAD+ 250 mg with fluids and vitamins, is $649.
How long does an NAD+ infusion take?
Plan on about 2 hours for 250 mg and 2 hours or more for 500 mg. NAD+ has to go in slowly, because running it faster tends to cause flushing, chest tightness or nausea.
What does an NAD+ IV feel like?
Many people feel warmth, flushing or a tight feeling in the chest or stomach at some point. It passes when the drip is slowed, so tell your provider right away.
Does NAD+ IV therapy work?
The honest answer is that research is early. Small studies show NAD+ can be infused safely when given slowly, but no large trials have proven it improves energy, focus or aging. Some clients like how they feel afterward, and your provider will talk through what it can and can't do for you.
Is NAD+ IV therapy FDA approved?
No. NAD+ infusions aren't FDA approved to treat any condition. We offer NAD+ as a wellness service with medical screening and supervision.
How often can I get NAD+?
There's no research-backed schedule. Your provider will suggest what makes sense for your goals and how you respond, and may recommend starting with one 250 mg infusion.
Is NAD+ IV better than NMN or NR supplements?
They're different. Supplements like NR and NMN are building blocks your body turns into NAD+, taken by mouth every day. An IV gives NAD+ directly under medical supervision. Neither has strong evidence for anti-aging benefits yet.
Can I combine NAD+ with other IV vitamins?
Yes. The Royal Palm Reserve combines NAD+ 250 mg with The Royal Palm drip and an extra liter of fluids. See the full IV therapy drip menu.
Does insurance cover NAD+ IV therapy?
No. NAD+ IV therapy is a cash-pay wellness service, and we don't bill insurance.
Medically reviewed by Dr. Andrei Gherghina, DO, board-certified by the American Board of Dermatology.
See prices for every treatment · Booking and first-visit FAQ


